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Omomyc is a mutant basic helixβloopβhelix leucine zipper (bHLHZip) domain which acts as a dominant negative and sequesters c-MYC in complexes preventing active transcription of c-MYC target genes while also allowing transcriptional repression ( in vitro and in vivo studies (Figure 1) and the limitations with current, anti-estrogen based treatment options for endometriosis, we evaluated the potential utility of Omomyc for endometriosis treatment
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