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In summary, S-biomolecules can increase in tissues and bloodstream from their absorption, from the diet or protein degradation (Met and Cys) under hormonal control but their constant levels are guaranteed by the biochemical S “fuel” represented by the Met cycle and transsulfuration, as verified through studies using in vivo Met tracers [18]

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Under specific conditions, excessive or dysregulated autophagy can lead to cell death, but this is generally considered an “abnormal” consequence of autophagy