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This mechanistic packaging comes primarily from the originating laboratory's papers, which have since received an Expression of Concern and a retraction (detailed in the Clinical Evidence section below), so it should be read as reported claims rather than settled pharmacology: HGF Potentiation: Dihexa binds to HGF and stabilizes its active conformation, increasing c-Met receptor activation at physiologically relevant HGF concentrations Synaptogenesis: The originating laboratory reported new synapse formation in hippocampal cultures at picomolar concentrations

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