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The dermis is the major constituent of the skin and is composed primarily of collagen, elastin, and glycosaminoglycans, which provide the skin its elasticity and flexibility (Figures 2A–E
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Astrocytic K + channels and transporters facilitate the spatial buffering of extracellular K + by internalizing excess K + in regions of heightened neuronal activity and redistributing it toward less active areas via gap junction-coupled astrocytic networks
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