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Chromatographic separation was achieved by UPLC (Agilent 1290, San Jose, CA, USA) on an AccQ-Tag Ultra column (Waters, Etten-Leur, The Netherlands) coupled to electrospray ionization on a triple quadrupole mass spectrometer (Agilent 6460, San Jose, CA, USA)
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By disrupting this interaction, researchers can study how senescent cell clearance affects aging processes, tissue function, and disease progression in controlled experimental settings
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