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p53 inhibits ferroptosis by reducing the accumulation of toxic lipid ROS and inducing the expression of cyclin-dependent kinase inhibitor 1A (CDKN1A/p21) (Figure 1) (Li and Li, 2020
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1.2.1.3 Complete removal of ubiquitin chains The complete removal of ubiquitin chains from ubiquitinated proteins generally results in protein stabilization by preventing it from UPS degradation [13, 23]
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