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The amelioration found in testicular abnormalities, poor spermatogenesis, disturbances in the reproductive system, redox imbalances, and increased cell death (39, 40) post-supplementation with MO extract emphasizes their potential in addressing reproductive problems
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In 1993, the first small-molecule ligands, L-692,429 and its superior derivative, L-163,191 (MK-0677), were developed, further accelerating research in this field (Table 1) (Smith et al., 1993
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